ATRX dysfunction induces replication defects in primary mouse cells.

Clynes, David; Jelinska, Clare; Xella, Barbara; Ayyub, Helena; Taylor, Stephen; Mitson, Matthew; Bachrati, Csanád Z; Higgs, Douglas R; Gibbons, Richard J

Clynes, David; Jelinska, Clare; Xella, Barbara; Ayyub, Helena; Taylor, Stephen; Mitson, Matthew; Bachrati, Csanád Z; Higgs, Douglas R; Gibbons, Richard J.

Afiliação

Clynes D; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Jelinska C; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Xella B; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Ayyub H; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Taylor S; Computational Biology Research Group, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Mitson M; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Bachrati CZ; School of Life Sciences, University of Lincoln, Brayford Pool, Lincoln, United Kingdom.
Higgs DR; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Gibbons RJ; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

PLoS One ; 9(3): e92915, 2014.

Article em En | MEDLINE | ID: mdl-24651726

Assuntos

DNA Helicases/metabolismo; Replicação do DNA; Proteínas Nucleares/metabolismo; Animais; Linhagem Celular; Montagem e Desmontagem da Cromatina; Quebras de DNA de Cadeia Dupla; Dano ao DNA; DNA Helicases/genética; Células-Tronco Embrionárias/metabolismo; Técnicas de Inativação de Genes; Humanos; Camundongos; Complexos Multiproteicos/metabolismo; Proteínas Nucleares/genética; Fase S; Telômero/metabolismo; Proteína Nuclear Ligada ao X

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article