p38&#945; MAPK is required for tooth morphogenesis and enamel secretion.

Greenblatt, Matthew B; Kim, Jung-Min; Oh, Hwanhee; Park, Kwang Hwan; Choo, Min-Kyung; Sano, Yasuyo; Tye, Coralee E; Skobe, Ziedonis; Davis, Roger J; Park, Jin Mo; Bei, Marianna; Glimcher, Laurie H; Shim, Jae-Hyuck

p38α MAPK is required for tooth morphogenesis and enamel secretion.

Greenblatt, Matthew B; Kim, Jung-Min; Oh, Hwanhee; Park, Kwang Hwan; Choo, Min-Kyung; Sano, Yasuyo; Tye, Coralee E; Skobe, Ziedonis; Davis, Roger J; Park, Jin Mo; Bei, Marianna; Glimcher, Laurie H; Shim, Jae-Hyuck.

Afiliação

Greenblatt MB; From the Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, mag3003@med.cornell.edu.
Kim JM; the Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065.
Oh H; the Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065.
Park KH; the Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065, the Department of Microbiology, Brain Korea 21 PLUS Project for Medical Sciences and Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Choo MK; the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129.
Sano Y; the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129.
Tye CE; the Department of Biochemistry, University of Vermont College of Medicine, Burlington, Vermont, 05405.
Skobe Z; the Forsyth Institute, Cambridge, Massachusetts 02142.
Davis RJ; the Howard Hughes Medical Institute and Program in Molecular Medicine, Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Park JM; the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129.
Bei M; the Department of Surgery, Massachusetts General Hospital, Shriners Burns Hospital, Harvard Medical School, Boston, Massachusetts 02115, and.
Glimcher LH; the Department of Medicine, Weill Cornell Medical College, New York, New York 10065.
Shim JH; the Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065, jas2060@med.cornell.edu.

J Biol Chem ; 290(1): 284-95, 2015 Jan 02.

Article em En | MEDLINE | ID: mdl-25406311

Assuntos

Ameloblastos/metabolismo; Esmalte Dentário/metabolismo; Regulação da Expressão Gênica no Desenvolvimento; Incisivo/metabolismo; Proteína Quinase 14 Ativada por Mitógeno/metabolismo; Odontogênese/genética; Ameloblastos/citologia; Amelogenina/genética; Amelogenina/metabolismo; Animais; Proteína Morfogenética Óssea 2/genética; Proteína Morfogenética Óssea 2/metabolismo; Proteína Morfogenética Óssea 7/genética; Proteína Morfogenética Óssea 7/metabolismo; Diferenciação Celular; Proliferação de Células; Esmalte Dentário/citologia; Esmalte Dentário/crescimento & desenvolvimento; Incisivo/citologia; Incisivo/crescimento & desenvolvimento; Integrina beta4/genética; Integrina beta4/metabolismo; MAP Quinase Quinase 3/genética; MAP Quinase Quinase 3/metabolismo; MAP Quinase Quinase 6/genética; MAP Quinase Quinase 6/metabolismo; Camundongos; Camundongos Transgênicos; Proteína Quinase 14 Ativada por Mitógeno/genética; Transdução de Sinais; Técnicas de Cultura de Tecidos; Quinases Ativadas por p21/genética; Quinases Ativadas por p21/metabolismo

Palavras-chave

Ameloblast; Bone Morphogenetic Protein (BMP); Ectodermal Dysplasia; Microtubule-associated Protein (MAP); SMAD Transcription Factor; Tooth Development; p38 MAPK

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article