[Serum hydrogen sulfide levels in children with benign infantile convulsions associated with mild gastroenteritis].
Zhongguo Dang Dai Er Ke Za Zhi
; 16(11): 1096-9, 2014 Nov.
Article
em Zh
| MEDLINE
| ID: mdl-25406550
ABSTRACT
OBJECTIVE:
To study the changes and significance of serum hydrogen sulfide (H2S) levels in children with benign infantile convulsions associated with mild gastroenteritis (BICE).METHODS:
Forty-two hospitalized children diagnosed with BICE were recruited to the observation group, and 46 children admitted due to acute gastroenteritis alone were recruited to the control group. Serum H2S levels were measured by a spectrophotometer.RESULTS:
The serum H2S level in the observation group was significantly lower than in the control group (28±12â µmol/L vs 45±10â µmol/L; P<0.01). The patients with a number of convulsions greater than or equal to two had significantly lower serum H2S levels than those with a number less than two (P<0.05). The number of convulsions was negatively correlated with serum H2S level in BICE patients (r=-0.485, P=0.001). When a convulsion exceeded 5 minues in duration, the duration was negatively correlated with serum H2S level (r=-0.736, P=0.004).CONCLUSIONS:
The reduction in endogenous H2S level might be one of the causes of convulsions in BICE patients. The degree of reduction in H2S level is associated with the number of convulsions and the duration of convulsion (when it exceeds 5 minues). Further investigation is needed to determine the clinical significance of these results.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Zh
Ano de publicação:
2014
Tipo de documento:
Article