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Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition.
Kuznetsov, Nikita A; Bergonzo, Christina; Campbell, Arthur J; Li, Haoquan; Mechetin, Grigory V; de los Santos, Carlos; Grollman, Arthur P; Fedorova, Olga S; Zharkov, Dmitry O; Simmerling, Carlos.
Afiliação
  • Kuznetsov NA; SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia Department of Natural Sciences, Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia.
  • Bergonzo C; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA.
  • Campbell AJ; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA.
  • Li H; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA.
  • Mechetin GV; SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia.
  • de los Santos C; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
  • Grollman AP; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
  • Fedorova OS; SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia Department of Natural Sciences, Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia fedorova@niboch.nsc.ru.
  • Zharkov DO; SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia Department of Natural Sciences, Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia dzharkov@niboch.nsc.ru.
  • Simmerling C; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY 11794, USA carlos.simmerling@stonybrook.edu.
Nucleic Acids Res ; 43(1): 272-81, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25520195
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article