Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts.

Wattanachanya, Lalita; Wang, Liping; Millard, Susan M; Lu, Wei-Dar; O'Carroll, Dylan; Hsiao, Edward C; Conklin, Bruce R; Nissenson, Robert A

Wattanachanya, Lalita; Wang, Liping; Millard, Susan M; Lu, Wei-Dar; O'Carroll, Dylan; Hsiao, Edward C; Conklin, Bruce R; Nissenson, Robert A.

Afiliação

Wattanachanya L; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA; Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospi
Wang L; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA. Electronic address: lipingwang05@yahoo.com.
Millard SM; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA. Electronic address: susan.millard@mater.uq.edu.au.
Lu WD; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA. Electronic address: weidar_lu@yahoo.com.
O'Carroll D; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA. Electronic address: dylancocarroll@gmail.com.
Hsiao EC; Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Francisco, CA, USA. Electronic address: Edward.Hsiao@ucsf.edu.
Conklin BR; Gladstone Institute of Cardiovascular Disease, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA. Electronic address: bconklin@gladstone.ucsf.edu.
Nissenson RA; Endocrine Research Unit, Veterans Affairs Medical Center and Departments of Medicine and Physiology, University of California, San Francisco, CA, USA. Electronic address: Robert.Nissenson@ucsf.edu.

Exp Cell Res ; 333(2): 289-302, 2015 May 01.

Article em En | MEDLINE | ID: mdl-25704759

Assuntos

Subunidades alfa Gs de Proteínas de Ligação ao GTP/fisiologia; Osteoblastos/metabolismo; Transcriptoma; Animais; Regeneração Óssea; Células Cultivadas; Fator 9 de Crescimento de Fibroblastos/genética; Fator 9 de Crescimento de Fibroblastos/metabolismo; Camundongos Transgênicos; Análise de Sequência com Séries de Oligonucleotídeos; Osteogênese; Receptores Acoplados a Proteínas G/genética; Receptores Acoplados a Proteínas G/metabolismo; Transdução de Sinais; Crânio/patologia; Crânio/fisiopatologia; Fator de Transcrição Sp7; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo

Palavras-chave

G protein coupled receptor (GPCR); Gene expression analysis; Intramembranous bone; Mouse model; Osteoblasts (OBs); Paracrine mediators

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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