Activation of AMPA receptor promotes TNF-&#945; release via the ROS-cSrc-NF&#954;B signaling cascade in RAW264.7 macrophages.

Cheng, Xiu-Li; Ding, Fan; Li, Hui; Tan, Xiao-Qiu; Liu, Xiao; Cao, Ji-Min; Gao, Xue

Activation of AMPA receptor promotes TNF-α release via the ROS-cSrc-NFκB signaling cascade in RAW264.7 macrophages.

Cheng, Xiu-Li; Ding, Fan; Li, Hui; Tan, Xiao-Qiu; Liu, Xiao; Cao, Ji-Min; Gao, Xue.

Afiliação

Cheng XL; Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Ding F; Office of Scientific R&D, Tsinghua University, Beijing, China.
Li H; Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Tan XQ; Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Liu X; Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Cao JM; Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. Electronic address: caojimin@126.com.
Gao X; Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. Electronic address: longlongnose@163.com.

Biochem Biophys Res Commun ; 461(2): 275-80, 2015 May 29.

Article em En | MEDLINE | ID: mdl-25871799

Assuntos

Macrófagos/imunologia; NF-kappa B/imunologia; Espécies Reativas de Oxigênio/imunologia; Receptores de AMPA/imunologia; Fator de Necrose Tumoral alfa/imunologia; Quinases da Família src/imunologia; Animais; Proteína Tirosina Quinase CSK; Linhagem Celular; Ativação de Macrófagos; Macrófagos/citologia; Camundongos; Transdução de Sinais

Palavras-chave

AMPA receptor; Inflammation; Macrophage; NF-κB; Reactive oxygen species; TNF-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article