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Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures.
Holmes, Avram J; Hollinshead, Marisa O; O'Keefe, Timothy M; Petrov, Victor I; Fariello, Gabriele R; Wald, Lawrence L; Fischl, Bruce; Rosen, Bruce R; Mair, Ross W; Roffman, Joshua L; Smoller, Jordan W; Buckner, Randy L.
Afiliação
  • Holmes AJ; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA ; Department of Psychology, Harvard University , Cambridge, MA 02138, USA ; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School , Boston, MA 02114, USA ; Athinoula A. Martinos Center for Biomedica
  • Hollinshead MO; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA ; Department of Psychology, Harvard University , Cambridge, MA 02138, USA ; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown,
  • O'Keefe TM; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA.
  • Petrov VI; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA.
  • Fariello GR; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA ; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School , Boston, MA 02114, USA.
  • Wald LL; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown, MA 02129, USA.
  • Fischl B; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown, MA 02129, USA.
  • Rosen BR; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown, MA 02129, USA.
  • Mair RW; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA ; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown, MA 02129, USA.
  • Roffman JL; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School , Boston, MA 02114, USA ; Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital and Harvard Medical School , Charlestown, MA 02129, USA.
  • Smoller JW; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School , Boston, MA 02114, USA.
  • Buckner RL; Center for Brain Science, Harvard University , Cambridge, MA 02138, USA ; Department of Psychology, Harvard University , Cambridge, MA 02138, USA ; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School , Boston, MA 02114, USA ; Athinoula A. Martinos Center for Biomedica
Sci Data ; 2: 150031, 2015.
Article em En | MEDLINE | ID: mdl-26175908
ABSTRACT
The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community data to probe these associations, a repository of structural and functional magnetic resonance imaging (MRI) scans linked to genetic information was constructed from a sample of healthy individuals. The initial release, detailed in the present manuscript, encompasses quality screened cross-sectional data from 1,570 participants ages 18 to 35 years who were scanned with MRI and completed demographic and health questionnaires. Personality and cognitive measures were obtained on a subset of participants. Each dataset contains a T1-weighted structural MRI scan and either one (n=1,570) or two (n=1,139) resting state functional MRI scans. Test-retest reliability datasets are included from 69 participants scanned within six months of their initial visit. For the majority of participants self-report behavioral and cognitive measures are included (n=926 and n=892 respectively). Analyses of data quality, structure, function, personality, and cognition are presented to demonstrate the dataset's utility.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article