Brain Performance versus Phase Transitions.
Sci Rep
; 5: 12216, 2015 Jul 20.
Article
em En
| MEDLINE
| ID: mdl-26193453
ABSTRACT
We here illustrate how a well-founded study of the brain may originate in assuming analogies with phase-transition phenomena. Analyzing to what extent a weak signal endures in noisy environments, we identify the underlying mechanisms, and it results a description of how the excitability associated to (non-equilibrium) phase changes and criticality optimizes the processing of the signal. Our setting is a network of integrate-and-fire nodes in which connections are heterogeneous with rapid time-varying intensities mimicking fatigue and potentiation. Emergence then becomes quite robust against wiring topology modification--in fact, we considered from a fully connected network to the Homo sapiens connectome--showing the essential role of synaptic flickering on computations. We also suggest how to experimentally disclose significant changes during actual brain operation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article