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PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.
Iansante, Valeria; Choy, Pui Man; Fung, Sze Wai; Liu, Ying; Chai, Jian-Guo; Dyson, Julian; Del Rio, Alberto; D'Santos, Clive; Williams, Roger; Chokshi, Shilpa; Anders, Robert A; Bubici, Concetta; Papa, Salvatore.
Afiliação
  • Iansante V; Cell Signaling and Cancer Laboratory, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, UK.
  • Choy PM; Cell Signaling and Cancer Laboratory, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, UK.
  • Fung SW; Department of Medicine, Section of Inflammation and Signal Transduction, Imperial College, London W12 0NN, UK.
  • Liu Y; The Sol Goldman Pancreatic Cancer Research Center, Division of Gastrointestinal and Liver Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
  • Chai JG; Department of Medical Oncology, Henan Cancer Hospital, Zhengzhou, Henan 450000, China.
  • Dyson J; Department of Medicine, Section of Molecular Immunology, Imperial College, London W12 0NN, UK.
  • Del Rio A; Department of Medicine, Section of Molecular Immunology, Imperial College, London W12 0NN, UK.
  • D'Santos C; Institute of Organic Synthesis and Photoreactivity, National Research Council, Bologna 40129, Italy.
  • Williams R; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge CB2 0RE, UK.
  • Chokshi S; Cell Signaling and Cancer Laboratory, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, UK.
  • Anders RA; Viral Hepatitis Laboratory, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, UK.
  • Bubici C; Viral Hepatitis Laboratory, Institute of Hepatology, Foundation for Liver Research, London WC1E 6HX, UK.
  • Papa S; The Sol Goldman Pancreatic Cancer Research Center, Division of Gastrointestinal and Liver Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
Nat Commun ; 6: 7882, 2015 Aug 10.
Article em En | MEDLINE | ID: mdl-26258887

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article