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Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial.
Thaçi, Diamant; Simpson, Eric L; Beck, Lisa A; Bieber, Thomas; Blauvelt, Andrew; Papp, Kim; Soong, Weily; Worm, Margitta; Szepietowski, Jacek C; Sofen, Howard; Kawashima, Makoto; Wu, Richard; Weinstein, Steven P; Graham, Neil M H; Pirozzi, Gianluca; Teper, Ariel; Sutherland, E Rand; Mastey, Vera; Stahl, Neil; Yancopoulos, George D; Ardeleanu, Marius.
Afiliação
  • Thaçi D; Comprehensive Center for Inflammation Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany. Electronic address: diamant.thaci@uksh.de.
  • Simpson EL; Department of Dermatology, Oregon Health and Science University, Portland, OR, USA.
  • Beck LA; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.
  • Bieber T; Department of Dermatology and Allergy, University of Bonn, Bonn, Germany.
  • Blauvelt A; Oregon Medical Research Center, Portland, OR, USA.
  • Papp K; K Papp Clinical Research and Probity Medical Research, Waterloo, ON, Canada.
  • Soong W; Alabama Allergy & Asthma Center, Birmingham, AL, USA.
  • Worm M; Department of Dermatology and Allergy, Charité University, Berlin, Germany.
  • Szepietowski JC; Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland.
  • Sofen H; UCLA School of Medicine, Los Angeles, CA, USA.
  • Kawashima M; Tokyo Women's Medical University, School of Medicine, Tokyo, Japan.
  • Wu R; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Weinstein SP; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Graham NM; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Pirozzi G; Sanofi, Bridgewater, NJ, USA.
  • Teper A; Sanofi, Bridgewater, NJ, USA.
  • Sutherland ER; Sanofi, Cambridge, MA, USA.
  • Mastey V; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Stahl N; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Ardeleanu M; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Lancet ; 387(10013): 40-52, 2016 Jan 02.
Article em En | MEDLINE | ID: mdl-26454361
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Ano de publicação: 2016 Tipo de documento: Article