Three-dimensional structure, binding, and spectroscopic characteristics of the monoclonal antibody 43.1 directed to the carboxyphenyl moiety of fluorescein.

Gayda, Susan; Longenecker, Kenton L; Judge, Russell A; Swift, Kerry M; Manoj, Sharmila; Linthicum, D Scott; Tetin, Sergey Y

Gayda, Susan; Longenecker, Kenton L; Judge, Russell A; Swift, Kerry M; Manoj, Sharmila; Linthicum, D Scott; Tetin, Sergey Y.

Afiliação

Gayda S; Diagnostics Research, Abbott Diagnostics Division, Abbott Park, IL, 60064.
Longenecker KL; Structural Biology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, 60064.
Judge RA; Structural Biology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, 60064.
Swift KM; Diagnostics Research, Abbott Diagnostics Division, Abbott Park, IL, 60064.
Manoj S; Diagnostics Research, Abbott Diagnostics Division, Abbott Park, IL, 60064.
Linthicum DS; Landcare Research, PO Box 40, Canterbury Agriculture and Science Centre, Gerald Street, Lincoln, New Zealand.
Tetin SY; Diagnostics Research, Abbott Diagnostics Division, Abbott Park, IL, 60064.

Biopolymers ; 105(4): 234-43, 2016 Apr.

Article em En | MEDLINE | ID: mdl-26756394

Assuntos

Anticorpos Monoclonais/química; Fluoresceína/química; Anticorpos Monoclonais/imunologia; Sítios de Ligação de Anticorpos; Cinética; Conformação Proteica; Termodinâmica

Palavras-chave

anti-fluorescein antibody; binding kinetics; binding thermodynamics; fluorescein; fluorescence spectroscopy; three-dimensional structure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article