Heparin Decreases in Tumor Necrosis Factor &#945; (TNF&#945;)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1.

Farwell, Sara Lynn N; Kanyi, Daniela; Hamel, Marianne; Slee, Joshua B; Miller, Elizabeth A; Cipolle, Mark D; Lowe-Krentz, Linda J

Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1.

Farwell, Sara Lynn N; Kanyi, Daniela; Hamel, Marianne; Slee, Joshua B; Miller, Elizabeth A; Cipolle, Mark D; Lowe-Krentz, Linda J.

Afiliação

Farwell SL; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015.
Kanyi D; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015, the Department of Chemistry, Lehigh University, Allentown, Pennsylvania 18103.
Hamel M; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015.
Slee JB; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015, the Department of Natural Sciences, DeSales University, Center Valley, Pennsylvania 18034.
Miller EA; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015.
Cipolle MD; the Department of Surgery, Lehigh Valley Hospital Center, Allentown, Pennsylvania 18103, and.
Lowe-Krentz LJ; From the Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania 18015, LJL0@lehigh.edu.

J Biol Chem ; 291(10): 5342-54, 2016 Mar 04.

Article em En | MEDLINE | ID: mdl-26769965

Assuntos

Fosfatase 1 de Especificidade Dupla/metabolismo; Células Endoteliais/metabolismo; Heparina/farmacologia; Receptores de Superfície Celular/metabolismo; Fibras de Estresse/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Animais; Bovinos; Linhagem Celular; Fosfatase 1 de Especificidade Dupla/genética; Células Endoteliais/efeitos dos fármacos; Endotélio Vascular/citologia; Humanos; MAP Quinase Quinase 4/metabolismo; Sistema de Sinalização das MAP Quinases; Proteínas de Membrana; Músculo Liso Vascular/citologia; Miócitos de Músculo Liso/efeitos dos fármacos; Miócitos de Músculo Liso/metabolismo; Ratos; Receptores de Superfície Celular/genética; Proteínas de Transporte Vesicular; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

JNK; actin; endothelial cell; heparin-binding protein; inflammation; p38 MAPK

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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