STAT5A is regulated by DNA damage via the tumor suppressor p53.

Mukhopadhyay, Utpal K; Cass, Jamaica; Raptis, Leda; Craig, Andrew W; Bourdeau, Véronique; Varma, Sonal; SenGupta, Sandip; Elliott, Bruce E; Ferbeyre, Gerardo

Mukhopadhyay, Utpal K; Cass, Jamaica; Raptis, Leda; Craig, Andrew W; Bourdeau, Véronique; Varma, Sonal; SenGupta, Sandip; Elliott, Bruce E; Ferbeyre, Gerardo.

Afiliação

Mukhopadhyay UK; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.
Cass J; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.
Raptis L; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.
Craig AW; Department of Biochemistry, Queens University, Kingston, Ontario, Canada.
Bourdeau V; Université de Montréal, Département de biochimie, Montréal, Québec H3C 3J7, Canada.
Varma S; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.
SenGupta S; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.
Elliott BE; Division of Cancer Biology and Genetics, Queen's University, Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada. Electronic address: elliottb@queensu.ca.
Ferbeyre G; Université de Montréal, Département de biochimie, Montréal, Québec H3C 3J7, Canada. Electronic address: g.ferbeyre@umontreal.ca.

Cytokine ; 82: 70-9, 2016 06.

Article em En | MEDLINE | ID: mdl-26876578

Assuntos

Neoplasias da Mama/metabolismo; Dano ao DNA; Mutação; Elementos de Resposta; Fator de Transcrição STAT5/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/genética; Feminino; Humanos; Células MCF-7; Fator de Transcrição STAT5/genética; Proteína Supressora de Tumor p53/genética; Proteínas Supressoras de Tumor/genética

Palavras-chave

DNA damage; STAT5; p53

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article