Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

Dash, Pramod K; Zhao, Jing; Kobori, Nobuhide; Redell, John B; Hylin, Michael J; Hood, Kimberly N; Moore, Anthony N

Dash, Pramod K; Zhao, Jing; Kobori, Nobuhide; Redell, John B; Hylin, Michael J; Hood, Kimberly N; Moore, Anthony N.

Afiliação

Dash PK; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030 p.dash@uth.tmc.edu.
Zhao J; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.
Kobori N; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.
Redell JB; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.
Hylin MJ; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.
Hood KN; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.
Moore AN; Department of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030.

J Neurosci ; 36(9): 2809-18, 2016 Mar 02.

Article em En | MEDLINE | ID: mdl-26937017

Assuntos

Barreira Hematoencefálica/fisiopatologia; Lesões Encefálicas/sangue; Lesões Encefálicas/patologia; Receptor Nicotínico de Acetilcolina alfa7/metabolismo; Análise de Variância; Animais; Lesões Encefálicas/complicações; Modelos Animais de Doenças; Encefalite/etiologia; Ensaio de Imunoadsorção Enzimática; Interleucina-1beta/sangue; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Permeabilidade; Peroxidase/metabolismo; Ratos; Ratos Sprague-Dawley; Fator de Necrose Tumoral alfa/sangue; Receptor Nicotínico de Acetilcolina alfa7/genética; Fator de von Willebrand/metabolismo

Palavras-chave

bloodbrain barrier breakdown; controlled cortical impact brain injury; inflammatory cytokines; secondary TBI pathology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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