Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice.

Zhang, Zhu-Qin; Ren, Si-Chong; Tan, Ying; Li, Zuo-Zhi; Tang, Xiaoqiang; Wang, Ting-Ting; Hao, De-Long; Zhao, Xiang; Chen, Hou-Zao; Liu, De-Pei

Zhang, Zhu-Qin; Ren, Si-Chong; Tan, Ying; Li, Zuo-Zhi; Tang, Xiaoqiang; Wang, Ting-Ting; Hao, De-Long; Zhao, Xiang; Chen, Hou-Zao; Liu, De-Pei.

Afiliação

Zhang ZQ; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Ren SC; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Tan Y; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Li ZZ; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Tang X; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Wang TT; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Hao DL; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Zhao X; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Chen HZ; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.
Liu DP; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 5 Dong Dan San Tiao, Beijing 100005, P.R. China.

Sci Rep ; 6: 23912, 2016 Apr 05.

Article em En | MEDLINE | ID: mdl-27045575

Assuntos

Apolipoproteínas E/genética; Epigênese Genética; Subfamília K de Receptores Semelhantes a Lectina de Células NK/genética; Placa Aterosclerótica/metabolismo; Sirtuínas/genética; Animais; Endarterectomia das Carótidas; Feminino; Fibroblastos/metabolismo; Heterozigoto; Humanos; Ligantes; Masculino; Camundongos; Camundongos Knockout; Regiões Promotoras Genéticas; Transdução de Sinais

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google