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Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation.
Das, Sudip; Lindemann, Claudia; Young, Bernadette C; Muller, Julius; Österreich, Babett; Ternette, Nicola; Winkler, Ann-Cathrin; Paprotka, Kerstin; Reinhardt, Richard; Förstner, Konrad U; Allen, Elizabeth; Flaxman, Amy; Yamaguchi, Yuko; Rollier, Christine S; van Diemen, Pauline; Blättner, Sebastian; Remmele, Christian W; Selle, Martina; Dittrich, Marcus; Müller, Tobias; Vogel, Jörg; Ohlsen, Knut; Crook, Derrick W; Massey, Ruth; Wilson, Daniel J; Rudel, Thomas; Wyllie, David H; Fraunholz, Martin J.
Afiliação
  • Das S; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Lindemann C; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Young BC; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom;
  • Muller J; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Österreich B; Institute of Molecular Infection Biology, University of Würzburg, D-97080 Wuerzburg, Germany;
  • Ternette N; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Winkler AC; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Paprotka K; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Reinhardt R; Max Planck Genome Centre, D-50829 Cologne, Germany;
  • Förstner KU; Institute of Molecular Infection Biology, University of Würzburg, D-97080 Wuerzburg, Germany;
  • Allen E; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Flaxman A; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Yamaguchi Y; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Rollier CS; Oxford Vaccine Group, University of Oxford, Oxford, United Kingdom;
  • van Diemen P; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Blättner S; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Remmele CW; Biocenter, Chair of Bioinformatics, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Selle M; Institute of Molecular Infection Biology, University of Würzburg, D-97080 Wuerzburg, Germany;
  • Dittrich M; Biocenter, Chair of Bioinformatics, University of Würzburg, D-97074 Wuerzburg, Germany; Institute of Human Genetics, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Müller T; Biocenter, Chair of Bioinformatics, University of Würzburg, D-97074 Wuerzburg, Germany;
  • Vogel J; Institute of Molecular Infection Biology, University of Würzburg, D-97080 Wuerzburg, Germany;
  • Ohlsen K; Institute of Molecular Infection Biology, University of Würzburg, D-97080 Wuerzburg, Germany;
  • Crook DW; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom;
  • Massey R; Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom;
  • Wilson DJ; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom thomas.rudel@biozentrum.uni-wuerzburg.de daniel.wilson@ndm.ox.ac.uk.
  • Rudel T; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany; thomas.rudel@biozentrum.uni-wuerzburg.de daniel.wilson@ndm.ox.ac.uk.
  • Wyllie DH; Jenner Institute, Centre for Molecular and Cellular Physiology, Oxford OX3 7BN, United Kingdom;
  • Fraunholz MJ; Biocenter, Chair of Microbiology, University of Würzburg, D-97074 Wuerzburg, Germany;
Proc Natl Acad Sci U S A ; 113(22): E3101-10, 2016 May 31.
Article em En | MEDLINE | ID: mdl-27185949
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article