Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes.

Hwang, Juyeon; Lee, Jocelyn A; Pallas, David C

Hwang, Juyeon; Lee, Jocelyn A; Pallas, David C.

Afiliação

Hwang J; From the Department of Biochemistry, Winship Cancer Center, and the Biochemistry, Cell, and Developmental Graduate Program, Emory University School of Medicine, Atlanta, Georgia 30322.
Lee JA; From the Department of Biochemistry, Winship Cancer Center, and the Biochemistry, Cell, and Developmental Graduate Program, Emory University School of Medicine, Atlanta, Georgia 30322.
Pallas DC; From the Department of Biochemistry, Winship Cancer Center, and the Biochemistry, Cell, and Developmental Graduate Program, Emory University School of Medicine, Atlanta, Georgia 30322 dpallas@emory.edu.

J Biol Chem ; 291(40): 21008-21019, 2016 Sep 30.

Article em En | MEDLINE | ID: mdl-27507813

Assuntos

Embrião de Mamíferos/enzimologia; Fibroblastos/enzimologia; Fosfoproteínas Fosfatases/metabolismo; Proteína O-Metiltransferase/metabolismo; Animais; Células Cultivadas; Histona Desacetilases/genética; Histona Desacetilases/metabolismo; Holoenzimas/genética; Holoenzimas/metabolismo; Metilação; Camundongos; Camundongos Knockout; Fosfoproteínas Fosfatases/genética; Fosforilação/genética; Proteína O-Metiltransferase/genética

Palavras-chave

Lcmt-1; PP4; PP6; methyltransferase; protein complex; protein methylation; protein phosphatase 2 (PP2A); protein phosphorylation; signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article