Evaluation of Tetrahydrobiopterin Therapy with Large Neutral Amino Acid Supplementation in Phenylketonuria: Effects on Potential Peripheral Biomarkers, Melatonin and Dopamine, for Brain Monoamine Neurotransmitters.

Yano, Shoji; Moseley, Kathryn; Fu, Xiaowei; Azen, Colleen

Yano, Shoji; Moseley, Kathryn; Fu, Xiaowei; Azen, Colleen.

Afiliação

Yano S; Genetics Division, Department of Pediatrics, LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.
Moseley K; Genetics Division, Department of Pediatrics, LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.
Fu X; Department of Pathology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.
Azen C; Clinical and Translational Science Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.

PLoS One ; 11(8): e0160892, 2016.

Article em En | MEDLINE | ID: mdl-27513937

Assuntos

Aminoácidos Neutros/uso terapêutico; Biopterinas/análogos & derivados; Suplementos Nutricionais; Fenilcetonúrias/tratamento farmacológico; Serotonina/metabolismo; Adulto; Biomarcadores/metabolismo; Biopterinas/efeitos adversos; Biopterinas/uso terapêutico; Dopamina/metabolismo; Dopamina/urina; Sinergismo Farmacológico; Feminino; Humanos; Masculino; Melatonina/sangue; Melatonina/metabolismo; Melatonina/urina; Pessoa de Meia-Idade; Fenilalanina/sangue

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google