[Male breast cancer: clinical, pathologic and immunohistochemical study].
Zhonghua Wai Ke Za Zhi
; 27(1): 28-30, 61, 1989 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-2776523
ABSTRACT
Forty-three cases of male breast cancer treated in the past 3 decades, comprising 1.92% of total cases of breast cancer in both sexes during the same period, were analyzed. Local skin involvement occurred in half of the patients. 67.7% of the patients presented axillary lymph node metastases and 82.9% were in stage II and III. Non-infiltrative and infiltrative specific cancers were diagnosed in 2 cases each, and infiltrative non-specific in 39 cases. Retrospective determination of estrogen receptor (ER) and carcinoembryonic antigen (CEA) in 33 specimens revealed positive ER in 57.6% and positive CEA in 72.7%. The more advanced the clinical stage, the higher is the positive rate of ER. Cases with positive CEA usually carried a more invasive process and a poorer prognosis. Immunohistochemical investigation in male breast cancer patients was valuable in the selection of post-operative adjuvant endocrine therapy or chemotherapy. Postoperative rise in serum CEA in patients with positive CEA may indicate recurrence.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Aged
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Aged80
/
Humans
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Male
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Middle aged
Idioma:
Zh
Ano de publicação:
1989
Tipo de documento:
Article