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Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-ß and cognitive function in APP/PS1 mice.
Dempsey, C; Rubio Araiz, A; Bryson, K J; Finucane, O; Larkin, C; Mills, E L; Robertson, A A B; Cooper, M A; O'Neill, L A J; Lynch, M A.
Afiliação
  • Dempsey C; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Rubio Araiz A; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Bryson KJ; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Finucane O; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Larkin C; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Mills EL; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland.
  • Robertson AAB; Institute for Molecular Bioscience, The University of Queensland, Australia.
  • Cooper MA; Institute for Molecular Bioscience, The University of Queensland, Australia.
  • O'Neill LAJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland.
  • Lynch MA; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland. Electronic address: lynchma@tcd.ie.
Brain Behav Immun ; 61: 306-316, 2017 Mar.
Article em En | MEDLINE | ID: mdl-28003153

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article