Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors.

Iurlaro, Raffaella; Püschel, Franziska; León-Annicchiarico, Clara Lucía; O'Connor, Hazel; Martin, Seamus J; Palou-Gramón, Daniel; Lucendo, Estefanía; Muñoz-Pinedo, Cristina

Iurlaro, Raffaella; Püschel, Franziska; León-Annicchiarico, Clara Lucía; O'Connor, Hazel; Martin, Seamus J; Palou-Gramón, Daniel; Lucendo, Estefanía; Muñoz-Pinedo, Cristina.

Afiliação

Iurlaro R; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
Püschel F; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
León-Annicchiarico CL; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
O'Connor H; Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin, Ireland.
Martin SJ; Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin, Ireland.
Palou-Gramón D; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
Lucendo E; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
Muñoz-Pinedo C; Cell Death Regulation Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain cmunoz@idibell.cat.

Mol Cell Biol ; 37(10)2017 05 15.

Article em En | MEDLINE | ID: mdl-28242652

Assuntos

Fator 4 Ativador da Transcrição/metabolismo; Apoptose; Estresse do Retículo Endoplasmático; Glucose/deficiência; Neoplasias/patologia; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/metabolismo; Regulação Neoplásica da Expressão Gênica; Células HCT116; Células HeLa; Humanos; Neoplasias/metabolismo; Fator de Transcrição CHOP/metabolismo

Palavras-chave

ATF4; TRAIL; apoptosis; cancer metabolism; glucose

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article