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A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications.
Fu, Xuan; Shang, Wenjing; Wang, Shuaishuai; Liu, Yunpeng; Qu, Jingyao; Chen, Xi; Wang, Peng George; Fang, Junqiang.
Afiliação
  • Fu X; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
  • Shang W; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
  • Wang S; Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA. pwang11@gsu.edu.
  • Liu Y; Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA. pwang11@gsu.edu.
  • Qu J; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
  • Chen X; Department of Chemistry, University of California, One Shields Avenue, Davis, CA 95616, USA.
  • Wang PG; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn and Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State U
  • Fang J; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
Chem Commun (Camb) ; 53(25): 3555-3558, 2017 Mar 23.
Article em En | MEDLINE | ID: mdl-28286894
ABSTRACT
Here, we developed a general strategy for synthesizing homogeneous HA conjugates, and generated homogeneous HA-pNP, HA-biotin, and HA-oroxylin conjugates to investigate the relationships between HA chain length and its diverse biological functions.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article