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Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.
Mpakali, Anastasia; Giastas, Petros; Deprez-Poulain, Rebecca; Papakyriakou, Athanasios; Koumantou, Despoina; Gealageas, Ronan; Tsoukalidou, Sofia; Vourloumis, Dionisios; Mavridis, Irene M; Stratikos, Efstratios; Saridakis, Emmanuel.
Afiliação
  • Mpakali A; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Giastas P; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Deprez-Poulain R; Univ. Lille, Inserm, Institut Pasteur de Lille , U1177-Drugs & Molecules for Living Systems, F-59000 Lille, France.
  • Papakyriakou A; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Koumantou D; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Gealageas R; Univ. Lille, Inserm, Institut Pasteur de Lille , U1177-Drugs & Molecules for Living Systems, F-59000 Lille, France.
  • Tsoukalidou S; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Vourloumis D; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Mavridis IM; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Stratikos E; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
  • Saridakis E; National Center for Scientific Research Demokritos , Agia Paraskevi, GR-15310 Athens, Greece.
ACS Med Chem Lett ; 8(3): 333-337, 2017 Mar 09.
Article em En | MEDLINE | ID: mdl-28337326
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article