Increased expression of the microRNA 106b~25 cluster and its host gene MCM7 in corticotroph pituitary adenomas is associated with tumor invasion and Crooke's cell morphology.

Garbicz, Filip; Mehlich, Dawid; Rak, Beata; Sajjad, Emir; Maksymowicz, Maria; Paskal, Wiktor; Zielinski, Grzegorz; Wlodarski, Pawel K

Garbicz, Filip; Mehlich, Dawid; Rak, Beata; Sajjad, Emir; Maksymowicz, Maria; Paskal, Wiktor; Zielinski, Grzegorz; Wlodarski, Pawel K.

Afiliação

Garbicz F; Laboratory of Centre for Preclinical Research, Department of Histology and Embryology, Medical University of Warsaw, Banacha 1B, 02-091, Warsaw, Poland.
Mehlich D; Laboratory of Centre for Preclinical Research, Department of Histology and Embryology, Medical University of Warsaw, Banacha 1B, 02-091, Warsaw, Poland.
Rak B; Laboratory of Centre for Preclinical Research, Department of Histology and Embryology, Medical University of Warsaw, Banacha 1B, 02-091, Warsaw, Poland.
Sajjad E; Postgraduate School of Molecular Medicine, Warsaw, Poland.
Maksymowicz M; Department of Internal Diseases and Endocrinology, Public Central Teaching Hospital Medical University of Warsaw, Warsaw, Poland.
Paskal W; Laboratory of Centre for Preclinical Research, Department of Histology and Embryology, Medical University of Warsaw, Banacha 1B, 02-091, Warsaw, Poland.
Zielinski G; Department of Neurosurgery, Military Institute of Medicine, Warsaw, Poland.
Wlodarski PK; Department of Pathology and Laboratory Diagnostics, M. Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.

Pituitary ; 20(4): 450-463, 2017 Aug.

Article em En | MEDLINE | ID: mdl-28432562

Assuntos

MicroRNAs/metabolismo; Componente 7 do Complexo de Manutenção de Minicromossomo/metabolismo; Neoplasias Hipofisárias/metabolismo; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Feminino; Humanos; Masculino; MicroRNAs/genética; Pessoa de Meia-Idade; Componente 7 do Complexo de Manutenção de Minicromossomo/genética; Recidiva Local de Neoplasia/genética; Recidiva Local de Neoplasia/metabolismo; Neoplasias Hipofisárias/genética; Reação em Cadeia da Polimerase em Tempo Real; Adulto Jovem

Palavras-chave

ACTHoma; Crooke's cell adenoma; MCM7; MiR-106b~25 cluster; MicroRNA; Pituitary adenoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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