Genetic variation of human neutrophil FcÎ³ receptors and SIRP&#945; in antibody-dependent cellular cytotoxicity towards cancer cells.

Treffers, Louise W; Zhao, Xi Wen; van der Heijden, Joris; Nagelkerke, Sietse Q; van Rees, Dieke J; Gonzalez, Patricia; Geissler, Judy; Verkuijlen, Paul; van Houdt, Michel; de Boer, Martin; Kuijpers, Taco W; van den Berg, Timo K; Matlung, Hanke L

Genetic variation of human neutrophil FcÎ³ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.

Treffers, Louise W; Zhao, Xi Wen; van der Heijden, Joris; Nagelkerke, Sietse Q; van Rees, Dieke J; Gonzalez, Patricia; Geissler, Judy; Verkuijlen, Paul; van Houdt, Michel; de Boer, Martin; Kuijpers, Taco W; van den Berg, Timo K; Matlung, Hanke L.

Afiliação

Treffers LW; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Zhao XW; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van der Heijden J; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Nagelkerke SQ; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Rees DJ; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Gonzalez P; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Geissler J; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Verkuijlen P; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Houdt M; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
de Boer M; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Kuijpers TW; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van den Berg TK; Emma Children's Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Matlung HL; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Eur J Immunol ; 48(2): 344-354, 2018 02.

Article em En | MEDLINE | ID: mdl-28952147

Assuntos

Citotoxicidade Celular Dependente de Anticorpos/genética; Antígenos de Diferenciação/genética; Neoplasias da Mama/genética; Genótipo; Imunoterapia/métodos; Neutrófilos/fisiologia; Receptores de IgG/genética; Receptores Imunológicos/genética; Antígenos de Diferenciação/metabolismo; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Neoplasias da Mama/imunologia; Antígeno CD47/metabolismo; Linhagem Celular Tumoral; Feminino; Predisposição Genética para Doença; Humanos; Desequilíbrio de Ligação; Polimorfismo Genético; Receptor ErbB-2/imunologia; Receptores de IgG/metabolismo; Receptores Imunológicos/metabolismo; Trastuzumab/farmacologia; Trastuzumab/uso terapêutico; Resultado do Tratamento

Palavras-chave

CD47- SIRPα interactions; Cancer; FcÎ³R; Neutrophils; Trastuzumab

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article