Proteomic identification of synaptic caspase substrates.

Victor, Ken G; Heffron, Daniel S; Sokolowski, Jennifer D; Majumder, Usnish; Leblanc, Andrea; Mandell, James W

Victor, Ken G; Heffron, Daniel S; Sokolowski, Jennifer D; Majumder, Usnish; Leblanc, Andrea; Mandell, James W.

Afiliação

Victor KG; Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Heffron DS; Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Sokolowski JD; Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Majumder U; Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Leblanc A; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Mandell JW; Department of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.

Synapse ; 72(1)2018 01.

Article em En | MEDLINE | ID: mdl-28960461

Assuntos

Caspases/metabolismo; Proteoma; Sinapses/metabolismo; Animais; Apoptose/efeitos dos fármacos; Apoptose/fisiologia; Western Blotting; Encéfalo/efeitos dos fármacos; Encéfalo/metabolismo; Caspases/administração & dosagem; Etanol/toxicidade; Humanos; Imuno-Histoquímica; Masculino; Espectrometria de Massas; Camundongos Endogâmicos C57BL; Proteínas Sensíveis a N-Etilmaleimida/metabolismo; Proteômica; Proteínas Recombinantes/administração & dosagem; Proteínas Recombinantes/metabolismo; Sinapses/efeitos dos fármacos; ATPases Vacuolares Próton-Translocadoras/metabolismo

Palavras-chave

apoptosis; caspase; cleavage; mass spectrometry; presynaptic; proteolytic; synaptic

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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