Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.

Hu, Chia-Wei; Worth, Matthew; Fan, Dacheng; Li, Baobin; Li, Hao; Lu, Lei; Zhong, Xiaofang; Lin, Ziqing; Wei, Liming; Ge, Ying; Li, Lingjun; Jiang, Jiaoyang

Hu, Chia-Wei; Worth, Matthew; Fan, Dacheng; Li, Baobin; Li, Hao; Lu, Lei; Zhong, Xiaofang; Lin, Ziqing; Wei, Liming; Ge, Ying; Li, Lingjun; Jiang, Jiaoyang.

Afiliação

Hu CW; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Worth M; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Fan D; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Li B; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Li H; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lu L; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Zhong X; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lin Z; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Wei L; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Ge Y; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Li L; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jiang J; Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Nat Chem Biol ; 13(12): 1267-1273, 2017 Dec.

Article em En | MEDLINE | ID: mdl-29058723

Assuntos

Sondas Moleculares/metabolismo; N-Acetilglucosaminiltransferases/metabolismo; Cristalografia por Raios X; Humanos; Cinética; Espectrometria de Massas; Modelos Moleculares; Conformação Molecular; Sondas Moleculares/síntese química; Sondas Moleculares/química; Mutação; N-Acetilglucosaminiltransferases/química; N-Acetilglucosaminiltransferases/genética; Especificidade por Substrato

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article