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Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.
Skalniak, Lukasz; Zak, Krzysztof M; Guzik, Katarzyna; Magiera, Katarzyna; Musielak, Bogdan; Pachota, Magdalena; Szelazek, Bozena; Kocik, Justyna; Grudnik, Przemyslaw; Tomala, Marcin; Krzanik, Sylwia; Pyrc, Krzysztof; Dömling, Alexander; Dubin, Grzegorz; Holak, Tad A.
Afiliação
  • Skalniak L; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Zak KM; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Guzik K; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Magiera K; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Musielak B; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Pachota M; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Szelazek B; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Kocik J; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Grudnik P; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Tomala M; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Krzanik S; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Pyrc K; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Dömling A; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
  • Dubin G; Department of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, 30-060 Krakow, Poland.
  • Holak TA; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.
Oncotarget ; 8(42): 72167-72181, 2017 Sep 22.
Article em En | MEDLINE | ID: mdl-29069777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article