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A potent hydroxamic acid-based, small-molecule inhibitor A452 preferentially inhibits HDAC6 activity and induces cytotoxicity toward cancer cells irrespective of p53 status.
Ryu, Hyun-Wook; Shin, Dong-Hee; Lee, Dong Hoon; Won, Hye-Rim; Kwon, So Hee.
Afiliação
  • Ryu HW; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
  • Shin DH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
  • Lee DH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
  • Won HR; Department of Integrated OMICS for Biomedical Science, Yonsei University, Seoul, Republic of Korea.
  • Kwon SH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
Carcinogenesis ; 39(1): 72-83, 2018 01 12.
Article em En | MEDLINE | ID: mdl-29106445
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article