Drug repurposing for the treatment of glioblastoma multiforme.

Abbruzzese, Claudia; Matteoni, Silvia; Signore, Michele; Cardone, Luca; Nath, Kavindra; Glickson, Jerry D; Paggi, Marco G

Abbruzzese, Claudia; Matteoni, Silvia; Signore, Michele; Cardone, Luca; Nath, Kavindra; Glickson, Jerry D; Paggi, Marco G.

Afiliação

Abbruzzese C; Department of Research, Advanced Diagnostics and Technological Innovation, Unit of Cellular Networks and Therapeutic Targets, Proteomics Area, Regina Elena National Cancer Institute, IRCCS, Via Elio Chianesi, 53, Rome, Italy.
Matteoni S; Department of Research, Advanced Diagnostics and Technological Innovation, Unit of Cellular Networks and Therapeutic Targets, Proteomics Area, Regina Elena National Cancer Institute, IRCCS, Via Elio Chianesi, 53, Rome, Italy.
Signore M; RPPA Unit, Proteomics Area, Core Facilities, Istituto Superiore di Sanità, Rome, Italy.
Cardone L; Department of Research, Advanced Diagnostics and Technological Innovation, Unit of Cellular Networks and Therapeutic Targets, Regina Elena National Cancer Institute, IRCCS, Rome, Italy.
Nath K; Laboratory of Molecular Imaging, Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Glickson JD; Laboratory of Molecular Imaging, Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Paggi MG; Department of Research, Advanced Diagnostics and Technological Innovation, Unit of Cellular Networks and Therapeutic Targets, Proteomics Area, Regina Elena National Cancer Institute, IRCCS, Via Elio Chianesi, 53, Rome, Italy. marco.paggi@ifo.gov.it.

J Exp Clin Cancer Res ; 36(1): 169, 2017 Nov 28.

Article em En | MEDLINE | ID: mdl-29179732

Assuntos

Antineoplásicos/uso terapêutico; Neoplasias Encefálicas/tratamento farmacológico; Glioblastoma/tratamento farmacológico; Antineoplásicos/química; Antineoplásicos/farmacologia; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/metabolismo; Ensaios Clínicos como Assunto; Reposicionamento de Medicamentos; Metabolismo Energético/efeitos dos fármacos; Redes Reguladoras de Genes/efeitos dos fármacos; Glioblastoma/genética; Glioblastoma/metabolismo; Humanos; Relação Estrutura-Atividade

Palavras-chave

Cancer treatment; Drug repositioning; Drug repurposing; Glioblastoma multiforme; High-throughput technologies; Signal transduction, Energy metabolism

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google