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Proteomics in Pathology.
Longuespée, Rémi; Casadonte, Rita; Schwamborn, Kristina; Reuss, David; Kazdal, Daniel; Kriegsmann, Katharina; von Deimling, Andreas; Weichert, Wilko; Schirmacher, Peter; Kriegsmann, Jörg; Kriegsmann, Mark.
Afiliação
  • Longuespée R; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Casadonte R; Proteopath GmbH, Trier, Germany.
  • Schwamborn K; Institute of Pathology, Technical University of Munich, Munich, Germany.
  • Reuss D; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Kazdal D; Clinical Cooperation Unit Neuropathology, German Cancer Center, Heidelberg, Germany.
  • Kriegsmann K; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • von Deimling A; Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
  • Weichert W; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Schirmacher P; Clinical Cooperation Unit Neuropathology, German Cancer Center, Heidelberg, Germany.
  • Kriegsmann J; Institute of Pathology, Technical University of Munich, Munich, Germany.
  • Kriegsmann M; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Proteomics ; 18(2)2018 01.
Article em En | MEDLINE | ID: mdl-29236356
ABSTRACT
Proteomic approaches are of growing importance in the biologist's toolbox. It greatly benefited from past and recent advances in sampling, chemical processing, mass spectrometry (MS) instrumentation, and data processing. MS-based analysis of proteins is now in the process of being translated in pathology for objective diagnoses. In this viewpoint, we present the workflows that we think are the most promising for applications in pathology. We also comment what we think are prerequisites for a successful translational implementation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article