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Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-ß.
Lan, Yan; Zhang, Dong; Xu, Chunxiao; Hance, Kenneth W; Marelli, Bo; Qi, Jin; Yu, Huakui; Qin, Guozhong; Sircar, Aroop; Hernández, Vivian M; Jenkins, Molly H; Fontana, Rachel E; Deshpande, Amit; Locke, George; Sabzevari, Helen; Radvanyi, Laszlo; Lo, Kin-Ming.
Afiliação
  • Lan Y; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA. yan.lan@emdserono.com kinming.lo@emdserono.com.
  • Zhang D; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Xu C; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Hance KW; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Marelli B; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Qi J; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Yu H; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Qin G; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Sircar A; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Hernández VM; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Jenkins MH; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Fontana RE; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Deshpande A; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Locke G; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Sabzevari H; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Radvanyi L; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA.
  • Lo KM; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA. yan.lan@emdserono.com kinming.lo@emdserono.com.
Sci Transl Med ; 10(424)2018 01 17.
Article em En | MEDLINE | ID: mdl-29343622
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article