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Antinociception of the spirocyclopiperazinium salt compound LXM-15 via activating α7 nAChR and M4 mAChR and inhibiting CaMKIIα/cAMP/CREB/CGRP signalling pathway in mice.
Yang, Hua; Sun, Qi; Liang, Yingying; Jiang, Yimin; Li, Runtao; Ye, Jia.
Afiliação
  • Yang H; Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Sun Q; Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Liang Y; Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Jiang Y; Center of Medical and Health Analysis, Peking University, Beijing, China.
  • Li R; Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Ye J; Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China. Electronic address: yejia@bjmu.edu.cn.
Regul Toxicol Pharmacol ; 94: 108-114, 2018 Apr.
Article em En | MEDLINE | ID: mdl-29353067
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article