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Long-term follow-up of surgical resection alone for primary intracranial rostrotentorial tumors in dogs: 29 cases (2002-2013).
Suñol, Anna; Mascort, Joan; Font, Cristina; Bastante, Alicia Rami; Pumarola, Martí; Feliu-Pascual, Alejandro Lujan.
Afiliação
  • Suñol A; Hospital Ars Veterinaria, carrer Cavallers nº37, 08034, Barcelona, Spain.
  • Mascort J; Hospital Ars Veterinaria, carrer Cavallers nº37, 08034, Barcelona, Spain.
  • Font C; Hospital Ars Veterinaria, carrer Cavallers nº37, 08034, Barcelona, Spain.
  • Bastante AR; Hospital Canis Girona. Carrer Can Pau Birol, 38. 17006 Girona, Spain.
  • Pumarola M; Neuroscience Institute of Barcelona. Universitat Autònoma de Barcelona, edifici M1, campus de Bellaterra E-98193, Cerdanyola del Vallès, Spain.
  • Feliu-Pascual AL; Department of Animal Medicine and Surgery, Veterinary Faculty, Universitat Autonoma de Barcelona, 08193 Bellaterra (Cerdanyola del Vallès), Barcelona, Spain.
Open Vet J ; 7(4): 375-383, 2017.
Article em En | MEDLINE | ID: mdl-29392117
Intracranial neoplasia is frequently encountered in dogs. After a presumptive diagnosis of intracranial neoplasia is established based on history, clinical signs and advanced imaging characteristics, the decision to treat and which treatment to choose must be considered. The objective of this study is to report survival times (ST) for dogs with intracranial meningiomas and gliomas treated with surgical resection alone (SRA), to identify potential prognostic factors affecting survival, and to compare the results with the available literature. Medical records of 29 dogs with histopathologic confirmation of intracranial meningiomas and gliomas treated with SRA were retrospectively reviewed. For each dog, signalment, clinical signs, imaging findings, type of surgery, treatment, histological evaluation, and ST were obtained. Twenty-nine dogs with a histological diagnosis who survived >7 days after surgery were included. There were 15 (52%) meningiomas and 14 (48%) gliomas. All tumors had a rostrotentorial location. At the time of the statistical analysis, only two dogs were alive. Median ST for meningiomas was 422 days (mean, 731 days; range, 10-2735 days). Median ST for gliomas was 66 days (mean, 117 days; range, 10-730 days). Kaplan-Meier analysis indicated that ST was significantly longer for meningiomas than for gliomas (P<0.05). A negative correlation between the presence of a midline shift and ST (P=0.037) and ventricular compression and ST (P=0.038) was observed for meningiomas. For gliomas, there were no significant associations between ST and any of the variables evaluated. In conclusion, the results of this study suggest that, for dogs that survived >7 days postoperatively, SRA might be an appropriate treatment, particularly for meningiomas, when radiation therapy is not readily available. Also, the presence of midline shift and ventricular compression might be negative prognostic factors for dogs with meningiomas.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article