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Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.
Forcellini, Elsa; Boutin, Sophie; Lefebvre, Carole-Anne; Shayhidin, Elnur Elyar; Boulanger, Marie-Chloé; Rhéaume, Gabrielle; Barbeau, Xavier; Lagüe, Patrick; Mathieu, Patrick; Paquin, Jean-François.
Afiliação
  • Forcellini E; PROTEO, CCVC, Département de chimie, Université Laval, Québec, QC G1V 0A6, Canada.
  • Boutin S; PROTEO, CCVC, Département de chimie, Université Laval, Québec, QC G1V 0A6, Canada.
  • Lefebvre CA; PROTEO, CCVC, Département de chimie, Université Laval, Québec, QC G1V 0A6, Canada.
  • Shayhidin EE; Laboratory of Cardiovascular Pathobiology, Quebec Heart and Lung Institute/Research Center, Département de chirurgie, Université Laval, Québec, QC, Canada.
  • Boulanger MC; Laboratory of Cardiovascular Pathobiology, Quebec Heart and Lung Institute/Research Center, Département de chirurgie, Université Laval, Québec, QC, Canada.
  • Rhéaume G; Laboratory of Cardiovascular Pathobiology, Quebec Heart and Lung Institute/Research Center, Département de chirurgie, Université Laval, Québec, QC, Canada.
  • Barbeau X; PROTEO, Département de biochimie, de microbiologie et de bio-informatique, Université Laval, Québec, QC G1V 0A6, Canada.
  • Lagüe P; PROTEO, Département de biochimie, de microbiologie et de bio-informatique, Université Laval, Québec, QC G1V 0A6, Canada.
  • Mathieu P; Laboratory of Cardiovascular Pathobiology, Quebec Heart and Lung Institute/Research Center, Département de chirurgie, Université Laval, Québec, QC, Canada.
  • Paquin JF; PROTEO, CCVC, Département de chimie, Université Laval, Québec, QC G1V 0A6, Canada. Electronic address: jean-francois.paquin@chm.ulaval.ca.
Eur J Med Chem ; 147: 130-149, 2018 Mar 10.
Article em En | MEDLINE | ID: mdl-29427906
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article