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Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement.
Ugurlar, Deniz; Howes, Stuart C; de Kreuk, Bart-Jan; Koning, Roman I; de Jong, Rob N; Beurskens, Frank J; Schuurman, Janine; Koster, Abraham J; Sharp, Thomas H; Parren, Paul W H I; Gros, Piet.
Afiliação
  • Ugurlar D; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.
  • Howes SC; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands.
  • de Kreuk BJ; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands.
  • Koning RI; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands.
  • de Jong RN; NeCEN, Gorlaeus Laboratories, Leiden University, 2333 CC Leiden, Netherlands.
  • Beurskens FJ; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands.
  • Schuurman J; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands.
  • Koster AJ; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands.
  • Sharp TH; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands.
  • Parren PWHI; NeCEN, Gorlaeus Laboratories, Leiden University, 2333 CC Leiden, Netherlands.
  • Gros P; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands. t.sharp@lumc.nl p.w.h.i.parren@lumc.nl p.gros@uu.nl.
Science ; 359(6377): 794-797, 2018 02 16.
Article em En | MEDLINE | ID: mdl-29449492
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article