The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin.

Wu, Xunwei; Tommasi di Vignano, Alice; Zhou, Qian; Michel-Dziunycz, Piotr J; Bai, Fuxiang; Mi, Jun; Qin, Jing; Zu, Tingjian; Hofbauer, Günther F L

Wu, Xunwei; Tommasi di Vignano, Alice; Zhou, Qian; Michel-Dziunycz, Piotr J; Bai, Fuxiang; Mi, Jun; Qin, Jing; Zu, Tingjian; Hofbauer, Günther F L.

Afiliação

Wu X; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.
Tommasi di Vignano A; Cutaneous Biology Research Centre, Massachusetts General Hospital, Charlestown, MA, United States of America.
Zhou Q; Cutaneous Biology Research Centre, Massachusetts General Hospital, Charlestown, MA, United States of America.
Michel-Dziunycz PJ; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.
Bai F; Department of Dermatology, University Hospital Zurich, Zürich, Switzerland.
Mi J; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.
Qin J; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.
Zu T; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.
Hofbauer GFL; Laboratory for Tissue Engineering and Regeneration and Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong, China.

PLoS Genet ; 14(5): e1007366, 2018 05.

Article em En | MEDLINE | ID: mdl-29723192

Assuntos

Calcineurina/metabolismo; Queratinócitos/metabolismo; Pele/metabolismo; Tristetraprolina/metabolismo; Animais; Animais Recém-Nascidos; Calcineurina/genética; Inibidores de Calcineurina/farmacologia; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/patologia; Células Cultivadas; Citocinas/genética; Citocinas/metabolismo; Feminino; Expressão Gênica/efeitos dos fármacos; Expressão Gênica/efeitos da radiação; Humanos; Mediadores da Inflamação/metabolismo; Queratinócitos/efeitos dos fármacos; Queratinócitos/efeitos da radiação; Camundongos Endogâmicos C57BL; Camundongos Knockout; Neoplasias Cutâneas/genética; Neoplasias Cutâneas/metabolismo; Neoplasias Cutâneas/patologia; Acetato de Tetradecanoilforbol/farmacologia; Tristetraprolina/genética; Raios Ultravioleta

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article