Metabolic profiles of neratinib in rat by using ultra-high-performance liquid chromatography coupled with diode array detector and Q-Exactive Orbitrap tandem mass spectrometry.

Liu, Wen; Li, Sha; Wu, Yangke; Yan, Xiao; Zhu, Y-M; Huang, J-H; Chen, Zhuo

Liu, Wen; Li, Sha; Wu, Yangke; Yan, Xiao; Zhu, Y-M; Huang, J-H; Chen, Zhuo.

Afiliação

Liu W; Department of Pharmacy, the People's Hospital of Hunan Province, Changsha, China.
Li S; Department of Pharmacy, Medical school of Hunan Normal University, Changsha, China.
Wu Y; Department of Pharmacy, Medical school of Hunan Normal University, Changsha, China.
Yan X; Department of Pharmacy, the People's Hospital of Hunan Province, Changsha, China.
Zhu YM; Department of Pharmacy, the People's Hospital of Hunan Province, Changsha, China.
Huang JH; Institute of Chinese Medicine, Hunan Academy of Traditional Chinese Medicine, Changsha, China.
Chen Z; Department of Medical Chemistry, XiangYa School of Pharmaceutical Science, Central South University, Changsha, China.

Biomed Chromatogr ; : e4272, 2018 May 03.

Article em En | MEDLINE | ID: mdl-29726026

Palavras-chave

metabolic pathway; metabolite identification; neratinib; rat

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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