The CCCH-type zinc finger transcription factor Zc3h8 represses NF-&#954;B-mediated inflammation in digestive organs in zebrafish.

Zou, Qingliang; Gang, Kai; Yang, Qifen; Liu, Xiaolin; Tang, Xuemei; Lu, Huiqiang; He, Jianbo; Luo, Lingfei

The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish.

Zou, Qingliang; Gang, Kai; Yang, Qifen; Liu, Xiaolin; Tang, Xuemei; Lu, Huiqiang; He, Jianbo; Luo, Lingfei.

Afiliação

Zou Q; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Gang K; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Yang Q; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Liu X; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Tang X; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Lu H; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
He J; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China.
Luo L; Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education, Southwest University, Beibei, 400715 Chongqing, China; Laboratory of Molecular Developmental Biology, School of Life Sciences, Southwest University, Beibei, 400715 Chongqing, China. Electronic address: lluo@swu.ed

J Biol Chem ; 293(31): 11971-11983, 2018 08 03.

Article em En | MEDLINE | ID: mdl-29871925

Assuntos

Hepatócitos/metabolismo; Fígado/metabolismo; NF-kappa B/genética; Pâncreas Exócrino/metabolismo; Fatores de Transcrição/genética; Proteínas de Peixe-Zebra/genética; Peixe-Zebra/genética; Sequência de Aminoácidos; Animais; Apoptose; Proliferação de Células; Citocinas/genética; Citocinas/metabolismo; Embrião não Mamífero; Regulação da Expressão Gênica no Desenvolvimento; Glutamina/metabolismo; Hepatócitos/patologia; Histidina/metabolismo; Inflamação; Intestinos/anormalidades; Intestinos/crescimento & desenvolvimento; Fígado/anormalidades; Fígado/crescimento & desenvolvimento; Macrófagos/metabolismo; Macrófagos/patologia; Mutação; NF-kappa B/metabolismo; Pâncreas Exócrino/anormalidades; Pâncreas Exócrino/crescimento & desenvolvimento; Fagocitose; Alinhamento de Sequência; Homologia de Sequência de Aminoácidos; Transdução de Sinais; Fatores de Transcrição/metabolismo; Peixe-Zebra/crescimento & desenvolvimento; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/metabolismo; Dedos de Zinco

Palavras-chave

NF-κ B (NF-κB); cell signaling; degeneration; digestive organ; inflammation; zebrafish; zinc finger

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article