A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion.
Immunity
; 49(1): 11-13, 2018 07 17.
Article
em En
| MEDLINE
| ID: mdl-30021140
Pancreatic adenocarcinoma (PDAC) is mostly refractory to immunotherapies. In this issue of Immunity, Li et al. (2018) generate a library of clonal PDAC tumors to examine the tumor-intrinsic features shaping the anti-tumor immune response and find that tumor cell-derived CXCL1 directly blunts T cell infiltration and reduces responsiveness to immunotherapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article