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The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies.
Rolvering, Catherine; Zimmer, Andreas D; Ginolhac, Aurélien; Margue, Christiane; Kirchmeyer, Mélanie; Servais, Florence; Hermanns, Heike M; Hergovits, Sabine; Nazarov, Petr V; Nicot, Nathalie; Kreis, Stephanie; Haan, Serge; Behrmann, Iris; Haan, Claude.
Afiliação
  • Rolvering C; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Zimmer AD; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Ginolhac A; University of Luxembourg, Life Sciences Research Unit-Bioinformatics Core Facility, Belvaux, Luxembourg.
  • Margue C; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Kirchmeyer M; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Servais F; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Hermanns HM; University Hospital Würzburg, Medical Clinic II, Division of Hepatology, Würzburg, Germany.
  • Hergovits S; University Hospital Würzburg, Medical Clinic II, Division of Hepatology, Würzburg, Germany.
  • Nazarov PV; Proteome and Genome Research Unit, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
  • Nicot N; Proteome and Genome Research Unit, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
  • Kreis S; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Haan S; University of Luxembourg, Life Sciences Research Unit-Molecular Disease Mechanisms Laboratory, Belvaux, Luxembourg.
  • Behrmann I; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
  • Haan C; University of Luxembourg, Life Sciences Research Unit-Signal Transduction Laboratory, Belvaux, Luxembourg.
J Leukoc Biol ; 104(5): 969-985, 2018 11.
Article em En | MEDLINE | ID: mdl-30040142

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article