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Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy.
Mousset, Charlotte M; Hobo, Willemijn; Ji, Yun; Fredrix, Hanny; De Giorgi, Valeria; Allison, Robert D; Kester, Michel G D; Falkenburg, J H Frederik; Schaap, Nicolaas P M; Jansen, Joop H; Gattinoni, Luca; Dolstra, Harry; van der Waart, Anniek B.
Afiliação
  • Mousset CM; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Hobo W; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Ji Y; Experimental Transplantation and Immunology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Fredrix H; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • De Giorgi V; Infectious Diseases Section, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Allison RD; Infectious Diseases Section, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Kester MGD; Department of Hematology - Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Falkenburg JHF; Department of Hematology - Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Schaap NPM; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Jansen JH; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Gattinoni L; Experimental Transplantation and Immunology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Dolstra H; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van der Waart AB; Department of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Oncoimmunology ; 7(10): e1488565, 2018.
Article em En | MEDLINE | ID: mdl-30288356
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article