Dose Optimization Based on Population Pharmacokinetic Modeling of High-Dose Cyclosporine, a P-glycoprotein Inhibitor, in Combination with Systemic Chemotherapy in Pediatric Patients with Retinoblastoma.

Ree, Yoon Sun; Back, Hyun-Moon; Yun, Hwi-Yeol; Ahn, Ji Hyun; Son, Eun Sun; Han, Jung Woo; Lyu, Chuhl Joo; Rhie, Sandy Jeong

Ree, Yoon Sun; Back, Hyun-Moon; Yun, Hwi-Yeol; Ahn, Ji Hyun; Son, Eun Sun; Han, Jung Woo; Lyu, Chuhl Joo; Rhie, Sandy Jeong.

Afiliação

Ree YS; 1 Graduate School of Clinical Health Sciences, Ewha Womans University , Seoul, Republic of Korea.
Back HM; 2 Department of Pharmacy, Yonsei University Health System , Seoul, Republic of Korea.
Yun HY; 3 College of Pharmacy, Chungnam National University , Daejeon, Republic of Korea.
Ahn JH; 3 College of Pharmacy, Chungnam National University , Daejeon, Republic of Korea.
Son ES; 2 Department of Pharmacy, Yonsei University Health System , Seoul, Republic of Korea.
Han JW; 2 Department of Pharmacy, Yonsei University Health System , Seoul, Republic of Korea.
Lyu CJ; 4 Division of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University Health System and College of Medicine, Yonsei University , Seoul, Republic of Korea.
Rhie SJ; 4 Division of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University Health System and College of Medicine, Yonsei University , Seoul, Republic of Korea.

J Ocul Pharmacol Ther ; 34(9): 647-655, 2018 11.

Article em En | MEDLINE | ID: mdl-30335563

Assuntos

Membro 1 da Subfamília B de Cassetes de Ligação de ATP/antagonistas & inibidores; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Ciclosporina/uso terapêutico; Soluções Oftálmicas/uso terapêutico; Retinoblastoma/tratamento farmacológico; Membro 1 da Subfamília B de Cassetes de Ligação de ATP/metabolismo; Criança; Pré-Escolar; Ciclosporina/farmacocinética; Coleta de Dados; Relação Dose-Resposta a Droga; Registros Eletrônicos de Saúde; Feminino; Humanos; Lactente; Masculino; Soluções Oftálmicas/farmacocinética; Retinoblastoma/diagnóstico; Estudos Retrospectivos

Palavras-chave

P-glycoprotein inhibitor; cyclosporine; pediatrics; population pharmacokinetics; retinoblastoma

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google