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Whole knee joint T1 values measured in vivo at 3T by combined 3D ultrashort echo time cones actual flip angle and variable flip angle methods.
Ma, Ya-Jun; Zhao, Wei; Wan, Lidi; Guo, Tan; Searleman, Adam; Jang, Hyungseok; Chang, Eric Y; Du, Jiang.
Afiliação
  • Ma YJ; Department of Radiology, University of California, San Diego, California.
  • Zhao W; Department of Radiology, University of California, San Diego, California.
  • Wan L; Department of Radiology, University of California, San Diego, California.
  • Guo T; Department of Radiology, University of California, San Diego, California.
  • Searleman A; Department of Radiology, University of California, San Diego, California.
  • Jang H; Department of Radiology, University of California, San Diego, California.
  • Chang EY; Department of Radiology, University of California, San Diego, California.
  • Du J; Radiology Service, VA San Diego Healthcare System, San Diego, California.
Magn Reson Med ; 81(3): 1634-1644, 2019 03.
Article em En | MEDLINE | ID: mdl-30443925
PURPOSE: To measure T1 relaxations for the major tissues in whole knee joints on a clinical 3T scanner. METHODS: The 3D UTE-Cones actual flip angle imaging (AFI) method was used to map the transmission radiofrequency field (B1 ) in both short and long T2 tissues, which was then used to correct the 3D UTE-Cones variable flip angle (VFA) fitting to generate accurate T1 maps. Numerical simulation was carried out to investigate the accuracy of T1 measurement for a range of T2 values, excitation pulse durations, and B1 errors. Then, the 3D UTE-Cones AFI-VFA method was applied to healthy volunteers (N = 16) to quantify the T1 of knee tissues including cartilage, meniscus, quadriceps tendon, patellar tendon, anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), marrow, and muscles at 3T. RESULTS: Numerical simulation showed that the 3D UTE-Cones AFI-VFA technique can provide accurate T1 measurements (error <1%) when the tissue T2 is longer than 1 ms and a 150 µs excitation RF pulse is used and therefore is suitable for most knee joint tissues. The proposed 3D UTE-Cones AFI-VFA method showed an average T1 of 1098 ± 67 ms for cartilage, 833 ± 47 ms for meniscus, 800 ± 66 ms for quadriceps tendon, 656 ± 43 ms for patellar tendon, 873 ± 38 ms for ACL, 832 ± 49 ms for PCL, 379 ± 18 ms for marrow, and 1393 ± 46 ms for muscles. CONCLUSION: The 3D UTE-Cones AFI-VFA method allows volumetric T1 measurement of the major tissues in whole knee joints on a clinical 3T scanner.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article