Integrated Analysis of Drug Sensitivity and Selectivity to Predict Synergistic Drug Combinations and Target Coaddictions in Cancer.

Jaiswal, Alok; Yadav, Bhagwan; Wennerberg, Krister; Aittokallio, Tero

Jaiswal, Alok; Yadav, Bhagwan; Wennerberg, Krister; Aittokallio, Tero.

Afiliação

Jaiswal A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Yadav B; Hematology Research Unit Helsinki (HRUH), University of Helsinki, Helsinki, Finland.
Wennerberg K; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Aittokallio T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. tero.aittokallio@helsinki.fi.

Methods Mol Biol ; 1888: 205-217, 2019.

Article em En | MEDLINE | ID: mdl-30519949

Assuntos

Antineoplásicos/farmacologia; Biologia Computacional/métodos; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Polifarmacologia; Combinação de Medicamentos; Sinergismo Farmacológico; Humanos; Software

Palavras-chave

Drug combinations; Drug polypharmacology; Drug sensitivity testing; Drugtarget interactions; Precision oncology; Target addictions; Target deconvolution

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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