Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors.

Widatalla, Sarrah E; Korolkova, Olga Y; Whalen, Diva S; Goodwin, J Shawn; Williams, Kevin P; Ochieng, Josiah; Sakwe, Amos M

Widatalla, Sarrah E; Korolkova, Olga Y; Whalen, Diva S; Goodwin, J Shawn; Williams, Kevin P; Ochieng, Josiah; Sakwe, Amos M.

Afiliação

Widatalla SE; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Korolkova OY; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Whalen DS; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Goodwin JS; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Williams KP; Department of Pharmaceutical Sciences and BRITE Institute, North Carolina Central University, Durham, NC, USA.
Ochieng J; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.
Sakwe AM; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA.

Carcinogenesis ; 40(8): 998-1009, 2019 08 22.

Article em En | MEDLINE | ID: mdl-30590459

Assuntos

Anexina A6/genética; Lapatinib/farmacologia; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Receptores ErbB/antagonistas & inibidores; Receptores ErbB/genética; Feminino; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Lapatinib/efeitos adversos; Fosforilação/efeitos dos fármacos; Inibidores de Proteínas Quinases/farmacologia; Transdução de Sinais/efeitos dos fármacos; Ativação Transcricional/efeitos dos fármacos; Neoplasias de Mama Triplo Negativas/genética; Neoplasias de Mama Triplo Negativas/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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