Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs.

Shu, Cindy C; Flannery, Carl R; Little, Christopher B; Melrose, James

Shu, Cindy C; Flannery, Carl R; Little, Christopher B; Melrose, James.

Afiliação

Shu CC; Raymond Purves Research Laboratory, Institute of Bone & Joint Research, North Sydney Area Health Authority, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia. Cindy.shu@sydney.edu.au.
Flannery CR; Bioventus LLC, 4721 Emperor Blvd., Suite 100, Durham, NC 27703, USA. carl.flannery@bioventusglobal.com.
Little CB; Raymond Purves Research Laboratory, Institute of Bone & Joint Research, North Sydney Area Health Authority, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia. Christopher.little@sydney.edu.au.
Melrose J; Sydney Medical School, Northern, Royal North Shore Hospital, St. Leonards, NSW 2065, Australia. Christopher.little@sydney.edu.au.

Int J Mol Sci ; 20(3)2019 Jan 29.

Article em En | MEDLINE | ID: mdl-30700002

Assuntos

Proteína ADAMTS4/metabolismo; Cartilagem Articular/metabolismo; Cartilagem Articular/patologia; Fibromodulina/metabolismo; Metaloproteinase 13 da Matriz/metabolismo; Animais; Humanos; Lumicana/metabolismo; Masculino; Pessoa de Meia-Idade; Osteoartrite do Joelho/metabolismo; Osteoartrite do Joelho/patologia; Ovinos

Palavras-chave

ADAMTS-4; DAMPs; FMOD; LUM; MMP-13; OA; PAMPs; SLRPs

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google