RhoA-Rho associated kinase signaling leads to renin-angiotensin system imbalance and angiotensin converting enzyme 2 has a protective role in acute pulmonary embolism.

Xu, Xiaoling; Shi, Liuhong; Ma, Xiuqing; Su, Hua; Ma, Guofeng; Wu, Xiaohong; Ying, Kejing; Zhang, Ruifeng

Xu, Xiaoling; Shi, Liuhong; Ma, Xiuqing; Su, Hua; Ma, Guofeng; Wu, Xiaohong; Ying, Kejing; Zhang, Ruifeng.

Afiliação

Xu X; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Shi L; Department of Ultrasound, the Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou, China.
Ma X; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Su H; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Ma G; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Wu X; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Ying K; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.
Zhang R; Department of Pulmonary and Critical Care Medicine, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China. Electronic address: zhangruifeng@zju.edu.cn.

Thromb Res ; 176: 85-94, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30784777

Assuntos

Peptidil Dipeptidase A/metabolismo; Embolia Pulmonar/metabolismo; Transdução de Sinais; Quinases Associadas a rho/metabolismo; Proteína rhoA de Ligação ao GTP/metabolismo; Doença Aguda; Enzima de Conversão de Angiotensina 2; Animais; Células Cultivadas; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Ratos Sprague-Dawley; Sistema Renina-Angiotensina

Palavras-chave

Acute pulmonary embolism; Angiotensin converting enzyme 2; Renin-angiotensin system; RhoA-Rho associated kinase signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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