Differential Effect of Glucose on ER-Mitochondria Ca<sup>2+</sup> Exchange Participates in Insulin Secretion and Glucotoxicity-Mediated Dysfunction of ß-Cells.

Dingreville, Florian; Panthu, Baptiste; Thivolet, Charles; Ducreux, Sylvie; Gouriou, Yves; Pesenti, Sandra; Chauvin, Marie-Agnès; Chikh, Karim; Errazuriz-Cerda, Elisabeth; Van Coppenolle, Fabien; Rieusset, Jennifer; Madec, Anne-Marie

Differential Effect of Glucose on ER-Mitochondria Ca²⁺ Exchange Participates in Insulin Secretion and Glucotoxicity-Mediated Dysfunction of ß-Cells.

Dingreville, Florian; Panthu, Baptiste; Thivolet, Charles; Ducreux, Sylvie; Gouriou, Yves; Pesenti, Sandra; Chauvin, Marie-Agnès; Chikh, Karim; Errazuriz-Cerda, Elisabeth; Van Coppenolle, Fabien; Rieusset, Jennifer; Madec, Anne-Marie.

Afiliação

Dingreville F; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Panthu B; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Thivolet C; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Ducreux S; Department of Endocrinology and Diabetes, Hospices Civils de Lyon, Hopital Lyon Sud, Pierre-Bénite, France.
Gouriou Y; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Pesenti S; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Chauvin MA; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Chikh K; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Errazuriz-Cerda E; Department of Endocrinology and Diabetes, Hospices Civils de Lyon, Hopital Lyon Sud, Pierre-Bénite, France.
Van Coppenolle F; CIQLE, Université Claude Bernard Lyon 1, Lyon, France.
Rieusset J; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France.
Madec AM; CarMeN Laboratory, INSERM, INRA, INSA, Université Claude Bernard Lyon 1, Oullins, France anne-marie.coquelet-madec@univ-lyon1.fr jennifer.rieusset@univ-lyon1.fr.

Diabetes ; 68(9): 1778-1794, 2019 09.

Article em En | MEDLINE | ID: mdl-31175102

Assuntos

Cálcio/metabolismo; Retículo Endoplasmático/efeitos dos fármacos; Glucose/farmacologia; Secreção de Insulina/efeitos dos fármacos; Células Secretoras de Insulina/efeitos dos fármacos; Mitocôndrias/efeitos dos fármacos; Animais; Linhagem Celular; Retículo Endoplasmático/metabolismo; Humanos; Células Secretoras de Insulina/metabolismo; Mitocôndrias/metabolismo; Ratos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article