Constitutive Expression of NRAS with Q61R Driver Mutation Activates Processes of Epithelial-Mesenchymal Transition and Leads to Substantial Transcriptome Change of Nthy-ori 3-1 Thyroid Epithelial Cells.

Demin, D E; Afanasyeva, M A; Uvarova, A N; Prokofjeva, M M; Gorbachova, A M; Ustiugova, A S; Klepikova, A V; Putlyaeva, L V; Tatosyan, K A; Belousov, P V; Schwartz, A M

Demin, D E; Afanasyeva, M A; Uvarova, A N; Prokofjeva, M M; Gorbachova, A M; Ustiugova, A S; Klepikova, A V; Putlyaeva, L V; Tatosyan, K A; Belousov, P V; Schwartz, A M.

Afiliação

Demin DE; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Afanasyeva MA; Moscow Institute of Physics and Technology, Moscow, 141701, Russia.
Uvarova AN; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Prokofjeva MM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Gorbachova AM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Ustiugova AS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Klepikova AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Putlyaeva LV; Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, 127051, Russia.
Tatosyan KA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.
Belousov PV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Schwartz AM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.

Biochemistry (Mosc) ; 84(4): 416-425, 2019 Apr.

Article em En | MEDLINE | ID: mdl-31228933

Assuntos

Transição Epitelial-Mesenquimal; GTP Fosfo-Hidrolases/metabolismo; Proteínas de Membrana/metabolismo; Neoplasias da Glândula Tireoide/genética; Transcriptoma; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; GTP Fosfo-Hidrolases/genética; Humanos; Proteínas de Membrana/genética; Mutagênese Sítio-Dirigida; Fenótipo; Transdução de Sinais; Fatores de Transcrição da Família Snail/metabolismo; Células Epiteliais da Tireoide/citologia; Células Epiteliais da Tireoide/metabolismo; Fatores de Transcrição Twist/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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